christian bailly inserm

Essential role of mitochondria in apoptosis of cancer ,

Essential role of mitochondria in apoptosis of cancer cells , Lamellarin D Caroline Ballot,1 Jérome Kluza,1 Alain Martoriati,1 Ulrika Nyman,2 Pierre Formstecher,1 Bertrand Joseph,2 Christian Bailly,1 and Philippe Marchetti1,3 1Inserm U837 and Faculté de Médecine, , INSERM, UNIVERSITÉ DE LILLE II and the Ligue Nationale...

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Mode of DNA Binding of Bis-Benzimidazoles and Related ,

Mode of DNA Binding of Bis-Benzimidazoles and Related Structures Studied by Electric Linear Dichroism Journal of Biomolecular Structure and Dynamics: Vol 12, No 1, pp 173-181 doi: 101080/07391102199410508095...

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Interaction with the DNA Minor Groove by Designed Minor ,

Interaction with the DNA Minor Groove by Designed Minor Groove Compounds: From Molecular Recognition to Therapeutics; Seminars Seminar Calendar , From Molecular Recognition to Therapeutics Friday, April 13, 2018 Dr W David Wilson , London (NATO Grant), with Dr Christian Bailly at the Institute of Cancer Research, Lille (INSERM ....

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Design and Optimization of Camptothecin Conjugates of ,

Paola B Arimondo, Alexandre Boutorine, Brigitte Baldeyrou, Christian Bailly, Masayasu Kuwahara, Sidney M Hecht, Jian-Sheng Sun, Thérése Garestier, Claude Héléne...

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Topoisomerase I and II Inhibitors Control Caspase-2 Pre ,

Topoisomerase I and II Inhibitors Control Caspase-2 Pre-Messenger RNA Splicing in Human Cells Ste´phanie Solier,1,2 Ame´lie Lansiaux,3 Emmanuelle Logette,1 Jane Wu,4 Johann Soret,5 Jamal Tazi,5 Christian Bailly,3 Lydie Desoche,1 Eric Solary,1 and Laurent Corcos1...

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Polo-like kinase 1 is overexpressed in acute myeloid ,

Polo-like kinase 1 is overexpressed in acute myeloid leukemia and its inhibition preferentially targets the proliferation of leukemic cells Annelies G Renner, Cédric Dos Santos, Christian Recher, Christian Bailly, Laurent Créancier, Anna Kruczynski, Bernard Payrastre , Stéphane Manenti, Inserm Unité 563, CPTP, Batiment B, CHU Purpan ....

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Synthesis, Crystal Structure and Interaction With DNA of N ,

Christian Bailly, 1 Bernard Viossat, 2 Xavier Labouze, 3 Georges Morgant, 3,4 Carmella Saturnino, 5 Jean Charles Lancelot, 5 Max Robba, 5 and Nguyen Huy Dung 3 1 Laboratoire de Pharmacologie Antitumorale du Centre Oscar Lambret and INSERM U-124, Place de Verdun, Lille, France...

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Topoisomerase I and II Inhibitors Control Caspase-2 Pre ,

Jan 01, 2004· Topoisomerase I and II Inhibitors Control Caspase-2 Pre-Messenger RNA Splicing in Human Cells 1 1This work was supported by the INSERM, the Conseil Régional de Bourgogne, the Ligue Nationale Française Contre le Cancer (E Solary and C Bailly) S Solier was financed by the University Hôpital du Bocage (Dijon)...

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WikiGenes - Christian Bailly

Christian Bailly INSERM Unité 124 et Laboratoire de Phamracologie Antitumorale Moléculaire du Centre Oscar Lambret Place de Verdun 59045 Lille France @*inserm,...

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The DNA-binding domain of human c-Abl tyrosine kinase ,

The DNA-binding domain of human c-Abl tyrosine kinase promotes the interaction of a HMG chromosomal , Michael J Waring2, Andrew A Travers1 and Christian Bailly* INSERM U ,...

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Publications Authored by Claude Houssier | PubFacts

Christian Bailly Carolina Carrasco Alexandra Joubert Christine Bal Nicole Wattez Marie-Paule Hildebrand Amélie Lansiaux Pierre Colson Claude Houssier Monica Cacho Ana Ramos Miguel F Braña , INSERM U-524 et Laboratoire de Pharmacologie Antitumorale du Centre Oscar Lambret, IRCL, Place de Verdun, 59045 Lille, France [email protected] lilleinsermfr ....

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Abstract A214: F14512, a novel targeted cytotoxic agent ,

Chemotherapy remains mainly used for the treatment of Acute Myelogenous Leukemia (AML) However, in the past 3 decades limited progress has been achieved in improving the long-term disease-free survival Therefore the development of more effective drugs for AML represents a high level of priority ....

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Sequence-selective binding to DNA of bis(amidinophenoxy ,

Biochemical Journal Apr 01, 1997, 323 (1) 23-31; DOI: 101042/bj3230023 Christian BAILLY INSERM U124, Institut de Recherches sur le Cancer, Place de Verdun, 59045 Lille...

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Synthesis and biological evaluation of novel ,

We report the synthesis and biological evaluation of new oxophenylarcyriaflavins designed as potential anticancer agents An efficient synthesis involving palladium-catalyzed Suzuki and Stille reactions is presented, without any indolic protective group The central ring closure of ,...

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Induction of unique structural changes in guanine-rich DNA ,

Krzysztof Lemke, 1, 4 Marcin Wojciechowski, 1 William Laine, 2 Christian Bailly, 2 Pierre Colson, 3 Maciej Baginski, 1 Annette K Larsen, 4 and Andrzej Skladanowski 1, * Krzysztof Lemke 1 Laboratory of Cellular and Molecular Pharmacology, Department of Pharmaceutical Technology and Biochemistry, Gdansk University of Technology, Gdansk, Poland...

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Topoisomerase I Poisons and Suppressors as Anticancer ,

Inhibitors of topoisomerase I constitute a novel family of antitumor agents The camptothecin derivatives topotecan and irinotecan represent new weapons in our arsenal for battling human cancer , Author(s):Christian Bailly Affiliation:INSERM Unite 524and Laboratoire de Pharmacologie Antitumorale du Centre OscarLambret , IRCL, Place de ....

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Topoisomerase I and II Inhibitors Control Caspase-2 Pre ,

Topoisomerase I and II Inhibitors Control Caspase-2 Pre-Messenger RNA Splicing in Human Cells Ste´phanie Solier,1,2 Ame´lie Lansiaux,3 Emmanuelle Logette,1 Jane Wu,4 Johann Soret,5 Jamal Tazi,5 Christian Bailly,3 Lydie Desoche,1 Eric Solary,1 and Laurent Corcos1...

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DNA Recognition by Quinoline Antibiotics: Use of Base ,

The luzopeptin antibiotics contain a cyclic decadepsipeptide to which are attached two quinoline chromophores that bisintercalate into DNA Although they bind DNA less tightly than the structurally related quinoxaline antibiotics echinomycin and triostin A, the molecular basis of their interaction ....

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Intercalation into DNA Is Not Required for Inhibition of ,

Intercalation into DNA Is Not Required for Inhibition of Topoisomerase I by Indolocarbazole Antitumor Agents Christian Bailly, Laurent Dassonneville, Pierre , Fax: 33-320-16-92-29; E-mail: bailly{at}lilleinsermfr , Intercalation into DNA Is Not Required for Inhibition of Topoisomerase I by Indolocarbazole Antitumor Agents Christian ....

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oradd14abs4 - cognizantcommunication

Pauline Huyghe, 1,2 * Laurent Dassonneville, 1 * Pierre Fenaux, 1,2 ** and Christian Bailly 1 1 INSERM U-524, Institut de Recherches sur le Cancer de Lille, 1 Place de Verdun, 59045 Lille cedex, France 2 Service des Maladies du Sang, Laboratoire d'Hématologie, CHU Lille...

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A tandem repeat of the SPKK peptide motif induces Ψ-type ,

Previous article in issue: Rabbit masseter expresses the cardiac α myosin heavy chain gene Previous article in issue: Rabbit masseter expresses the cardiac α myosin heavy chain gene Next article in issue: A negative charge in the M2 transmembrane segment of the neuronal α7 acetylcholine receptor ....

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Strategies and challenges for the next generation of ,

Christian Bailly is the Managing Director at CIPF He obtained his PhD in life sciences at the University of Lille, France, in 1989, and completed a postdoctoral position in the department of ....

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Current Medicinal Chemistry Topoisomerase I Poisons and ,

Topoisomerase I Poisons and Suppressors as Anticancer Drugs Christian Bailly* INSERM Unité 524 and Laboratoire de Pharmacologie Antitumorale du Centre Oscar Lambret , IRCL, Place de Verdun, 59045 Lille, France Abstract : Inhibitors of topoisomerase I constitute a novel family of antitumor agents...

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9th International Conference on Environmental Mutagens ,

Sep 03, 2005· Christian Bailly, INSERM, IRCL, Lille, France : Postreplicative Protection against Induction of Mutations by 8oxodG-induced Mutagenesis in Mammalian Cells Masaaki Moriya, State University at Stony Brook, New York, NY, USA : Recombination Repair and a Treatment for BRCA2 Tumors Thomas Helleday, University of Sheffield, Sheffield, UK : 3:30 pm...

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Calories from carbohydrates: energetic contribution of the ,

Christian Baillyl, Xiaogang Qu*, David E Graves3, Michelle Prudhomme4 and Jonathan B Chaires* Background: Only a few antitumor drugs inhibit the DNA breakage-reunion , [email protected] Key words: carbohydrate-DNA recognition, indolocarbazole, rebeccamycin, stereospecificity, topoisomerase I Received: 15 January 1999...

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Graphical Abstracts, Bioorganic & Medicinal Chemistry | 10 ,

Read "Graphical Abstracts, Bioorganic & Medicinal Chemistry" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips , Pascale Moreau,a Nathalie Gaillard,a Christelle Marminon,a Fabrice Anizon,a Nathalie Dias,b Brigitte Baldeyrou,b ´ Christian Bailly,lain ....

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Read topoI_CMC2000pdf

Christian Bailly* INSERM Unité 524 and Laboratoire de Pharmacologie Antitumorale du Centre Oscar Lambret , IRCL, Place de Verdun, 59045 Lille, France Abstract: Inhibitors of topoisomerase I constitute a novel family of antitumor agents...

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christian bailly inserm - prodorecoza

View the profiles of professionals named Christian Bailly on LinkedIn There are 45 professionals named Christian Bailly, who use LinkedIn to exchange information, ideas, and opportuniti There are 45 professionals named Christian Bailly, who use LinkedIn to exchange information, ideas, and opportuniti More Reading...

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Briefreport Polo ,

MYELOID NEOPLASIA Briefreport Polo-likekinase1isoverexpressedinacutemyeloidleukemiaanditsinhibition preferentiallytargetstheproliferationofleukemiccells...

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Publications Authored by Christian Bailly | PubFacts

Christian Bailly Reem K Arafa Farial A Tanious William Laine Christéle Tardy Amélie Lansiaux Pierre Colson David W Boykin W David Wilson Biochemistry 2005 Feb;44(6):1941-52 INSERM U-524 et Laboratoire de Pharmacologie Antitumorale du Centre Oscar Lambret, IRCL, 59045 Lille, France...

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